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Extra resources for A Bayesian Approach to Weibull Survival Models - Application to a Cancer Clinical Trial

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The data were centrally processed, and there was an overall coordinating center for the operations. 30 Davis and Ford Table 1 HDFP Inclusion and Exclusion Criteria Inclusion Criteria 1. Men and women aged 30–69 years 2. Average home screening DBP Ն 95 mm Hg 3. Confirmed follow-up DBP Ն 90 mm Hg Exclusion Criteria 1. Terminally ill patients 2. Institutionalized patients The trial used a method of organization similar to that recommended by a committee of the National Advisory Heart Council (Fig.

Measures were undertaken to ensure maximum clinic attendance and medication adherence. These included short waiting times, conveniently scheduled appointments, provision of transpor- Hypertension Detection and Follow-Up Program 33 tation services if needed, and a program physician availability at all times for hypertensionrelated problems. Antihypertensive drug treatment was administered according to a standardized protocol. Participants with an entry DBP of 100 mm Hg or more or who were already on antihypertensive medication were assigned a goal pressure of 90 mm Hg or less, whereas those whose entry DBP ranged from 90 to 99 mm Hg were to achieve at least a 10 mm Hg reduction.

Follow-Up Stepped Care participants were seen at intervals determined by their clinic status, but at least every four months and generally every two months. All SC and RC participants were seen at home at years 1, 2, 4, and 5 for a health history and BP measurements and at the clinic at years 2 and 5 for an examination similar to that at entry to the study. At each contact, any RC participant with DBP still 90 mm Hg or higher was advised to visit a physician. If severe hypertension (DBP 115 mm Hg or higher) or major organ system damage was present, special steps were taken to achieve contact with a physician.

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